Invitation
Continuous renal replacement therapy (CRRT) is routinely administered in Intensive Care Units in the UK. Previous studies compared different clearance rates and concluded that there was no mortality benefit with more intensive CRRT. As a result, current international guidelines recommend to deliver a CRRT dose (effluent flow rate) of 20 - 25ml/kg/hr. However, results from observational studies (mainly from Japan) suggest that lower doses at 10-15ml/kg/hr may be sufficient without putting patients at risk but these doses have not been investigated in randomised controlled trials. If lower doses are indeed sufficient and safe, less dialysis fluid will be needed and patients will lose less essential minerals and medications during CRRT. This will also decrease the work load of the nurses, generate less waste and save money, and it may help kidneys recovering better. Thus, there is a need for more research in this area.
In preparation for a potential future randomized controlled trial, we would like to explore current practice of CRRT dosing in ICUs in the UK. We would like to invite you to participate in a short questionnaire to understand better how doctors, nurses and colleagues currently prescribe CRRT in the ICU.
The questionnaire is fully anonymised and no personal data will be collected. It will take less than 5 minutes to complete. The questionnaire is held on a secure platform. Consent is implied by the completion of the survey. The data will be analysed by Professor M Ostermann from Guy’s & St Thomas’ Hospital in London, UK, and be used to inform a future clinical trial.
For further information, please contact M Ostermann at:
For further information, please contact M Ostermann at:
Guy’s & St Thomas NHS Foundation Hospital, Department of Critical Care, Westminster Bridge Road, London SE1 7EH, UK
Email: Marlies.Ostermann@gstt.nhs.uk
Thank you for your participation.