Symptom Questionnaire
1.
Is dry skin, eyes, and/or mucus membranes a frequent symptom?
Yes
No
Moderate
Unknown
2.
Symptoms include history of or current problems with nonhealing cracks/fissures at the corners of the lips (cheilitis).
Yes
No
Unknown
3.
Symptoms include history of or current problems with overall skin dryness and/or pruritus - peeling skin on the palms and soles, and fingertip fissuring.
Yes
No
Moderate
Unknown
4.
Symptoms include history of or current problems with thinning hair and/or hair loss without scarring (Telogen effluvium).
Yes
No
Moderate
Unknown
5.
Symptoms include bone spurs, calcinosis (calcium deposits in the skin and subcutaneous tissue), and/or hypercalcemia. Over the long term osteoporosis and hip fractures may be a concern.
Yes
No
Unknown
6.
Symptoms may include headache, nausea, and vomiting.
Yes
No
Headache
Nausea and/or vomiting
Unknown
7.
Symptoms of increased pressure around the brain may be a cause of severe headaches and/or may affect vision, narrowing of the field of view, (pseudotumor cerebri syndrome).
Yes
No
Unknown
8.
Symptoms include hypothyroidism, or intermittent problems with thyroid function. Undiagnosed issues of low thyroid function might include thinning hair, feeling cold easily, depression, apathy, gaining excess weight easily, feeling very tired easily, constipation.
Yes
No
Unknown
9.
Symptoms include hypertriglyceridemia and other blood lipid changes.
Yes
No
Unknown
10.
Symptoms include a history or current problem of acute hemorrhagic pancreatitis.
Yes
No
Unknown
11.
Symptoms include history of or current renal/kidney dysfunction.
Yes
No
Unknown
12.
Symptoms include history of or current problems of elevated serum transaminases, or chronically with liver damage leading to fibrosis and hepatic stellate cell activation.
Yes
No
Unknown
13.
Symptoms include mental confusion, irritability, anxiety, depression, and/or suicidal ideation, and/or more extreme psychosis or suicide attempts.
Anxiety
Depression
Irritability/agitation/confusion
Irrational thinking/Psychosis
Suicidal ideation
Suicidal attempt
Suicide, form being completed for the patient
None of the above
Unknown
14.
Symptoms include mitochondrial dysfunction and/or oxidative stress (symptoms might include fatigue, muscle cramps, fibromyalgia).
Yes
No
Unknown
15.
Symptoms include increased β-amyloid1-40 peptide (the protein tangles that may be elevated in the brain of patients with Alzheimer's dementia or sometimes in autism).
Yes
No
Unknown
16.
Symptoms include dopamine imbalance and may include low dopamine: "tremor, stiffness, slowness of spontaneous movement, poor balance, and poor coordination"; and/or elevated dopamine: "high libido (sex drive), anxiety, difficulty sleeping, increased energy, mania, stress, and improved ability to focus and learn" and muscle twitches may occur.
Symptoms of low dopamine.
Symptoms of elevated dopamine.
Symptoms may include both types of problems at different times.
No symptoms of dopamine imbalance.
Unknown
17.
I (or the patient) have had a history of psychiatric or other medication use.
No
Retinoid medication, such as bexarotene, isotretinoin, etretinate, and acitretin
Unknown
Other Medication history (please specify)
18.
Akathisia symptoms have been a problem (repetitive motions, largely uncontrollable, may also have mental symptoms of anxiety or agitation).
Yes
No
Unknown
19.
Mast Cell Activation Syndrome or histamine excess has been a problem (seasonal allergy or allergy like symptoms and food intolerances somewhat frequently).
Yes
No
Unknown
20.
I (or the patient) have had a history of an adverse vaccine reaction.
Yes
No
21.
Has there been a history of a viral or other type of infection with chronic stages such as Lyme's Disease, Epstein Barr virus, or SARS-CoV-2 (COVID19)?
Yes
No
Unknown
Infection history (please specify)
22.
Meals and snacks include meats, poultry, fish, milk and other dairy products.
Several servings per day typically
At least one serving per day
At least one serving per week
One serving per month or less
No servings of animal products typically
Unknown
23.
Meals and snacks include carrots, tomato products (fresh, or tomato sauce, ketchup, or salsa), sweet potatoes, winter squash or pumpkin, dark green leafy vegetables, cantaloupe, apricots, mango, papaya, peaches, nectarines.
Several servings per day typically.
At least one serving every other day
At least one serving per week
One serving or less per month
No servings of carotenoid rich plant foods typically
Unknown
24.
Vitamin A and/or Beta-carotene is taken as a supplement singly or in one-a-day vitamins daily.
Yes
No
Weekly
Monthly
Unknown
25.
Retinoid toxicity - excess of the active form of vitamin A - has been identified with retinoid medication treatment. Stopping retinoid medication use helps. Theoretically liver injury may cause an increase in vitamin A being activated in the liver & lead to toxicity symptoms also. Reducing vitamin A in the diet or supplements may be needed. Whether that is true and how to heal the liver so less vitamin A is activated would be a question for more research. Thanks for participating in this early stage of information gathering.
I was familiar with the symptoms of retinoid toxicity.
I was not familiar with the symptoms of retinoid toxicity.
26.
Demographic information: What is your genetic sex (or the patient's)?
Male
Female
Prefer not to answer.
27.
What is your gender (or the patient's)?
Male
Female
Nonbinary
Asexual
Prefer not to answer.
28.
What is your age (or the patient's age)?
17 or younger
18 to 24
25 to 34
35 to 44
45 to 54
55 to 64
65 to 74
75 or older
29.
What is your (or the patient's) race or ethnicity?
Asian
Black or African American
Hispanic or Latino
Middle Eastern or North African
Multiracial or Multiethnic
Native American or Alaska Native
Native Hawaiian or other Pacific Islander
White
Another race or ethnicity, please describe below
Self-describe below:
30.
This survey is being completed about your own symptoms or on behalf of someone else? Thank you very much for participating in this survey.
Survey answers are about myself
Survey answers are about my child.
Survey answers are about a patient.
Survey answers are about a deceased person.
Survey answers are about a friend or some other person being helped. Thank you!
Current Progress,
0 of 30 answered