2019 Fall Rapid Integration Post-Test
1.
48-yr-woman presents for restaging of lymphoma after chemotherapy. She has a history of skin itching and hives after contrast CT last time. What is the next best step.
Do a contrast CT
Do a non-contrast CT
Do a contrast CT after premedication
Do a contrast CT after hydration
2.
52-year-woman with history of breast cancer treated 5 years back and gall stones. Now presents with acute right upper abdominal pain and fever. What is the next best imaging test?
Radiograph
Ultrasound
CT
MR
3.
If a patient is randomized to a placebo arm on study they will receive less treatment than the standard of care?
True
False
4.
What type of research is most commonly seen/used in Oncology treatment?
Case Reports
Meta-analysis
Systematic Review
Randomized and Non-Randomized Clinical Trials
5.
Which phase of research includes about 200 patient's and focuses on checking for efficacy?
Phase 1
Phase 2
Phase 3
Phase 4
6.
Which Oncologic Emergency is referenced by the following phrase: “Stones, Bones, Moans, Groans, Thrones, Psychiatric Overtones”?
Superior Vena Cava Syndrome
Increased Intracranial Pressure
Hypercalcemia of Malignancy
Hyperviscosity Syndrome
7.
A 50 year old patient with metastatic breast cancer presents with an onset of back pain, motor weakness and decreased buttocks sensation. You are concerned about spinal cord compression. You give her Dexamethasone 10 mg IV x 1. What is the next step that you would do?
Radiation Oncology Consult
Neurosurgery Consult
Consult both Radiation and Neurosurgery immediately
Wait for MRI results before you consult a service
8.
Which oncologic emergency is characterized by hyperuricemia, hyperkalemia, hypocalcemia and renal failure?
Neutropenic Fever
Hypercalcemia of Malignancy
Tumor Lysis Syndrome
Hyperviscosity Syndrome
9.
XY is a 60 y/o female with Stage IV TNBC and showed PD-L1 > 1%. She was recently started on atezolizumab 840 mg Days 1 and 15 alongside nab-PACLitaxel 100 mg/m2 Days 1,8, and 15 every 28 days. What side effects concern you and how would you monitor?
Increases in blood pressure; monitor BP at home and before infusion
Hepatotoxicity; monitor LFTs prior to each dose
Extravasation; monitor injection site during administration
Hypothyroidism or thyrotoxicosis; monitor TSH on Day 1 of each cycle
II and IV
10.
BW is a 70 y/o male recently with an unresectable nodal melanoma lesion recurrent after initial surgery. He will be started on talimogene laherparepvec. What precautions would you recommend BW to take while receiving this therapy?
May experience influenza-like illness, and injection site pain
Could develop herpetic infections and should follow standard hygienic practices to prevent viral transmission
Will need to adjust dose in renal or liver dysfunction
This therapy is localized and therefore not associated with major toxicity
I and II
11.
WW is a 67 y/o male that was recently diagnosed with advanced non squamous NSCLC w PD-L1 expression ≥ 1% and EGFR/ALK negative. His oncology team started him on atezolizumab 1,200 mg, bevacizumab 15 mg/kg, PACLitaxel 200 mg/m2, and CARBOplatin AUC 6 every 21 days for 4 cycles. What side effects concern you and how would you monitor?
Increases in blood pressure; monitor BP at home and before infusion
Hepatotoxicity; monitor LFTs prior to each dose
Extravasation; monitor injection site during administration
Hypothyroidism or thyrotoxicosis; monitor TSH on Day 1 of each cycle
All of the above
12.
What treatment is FDA approved for newly diagnosed FLT 3+ acute myeloid leukemia?
Idhifa
Venetoclax
Vyxeos
Midostaruin
13.
Which drug below is approved for newly diagnosed CD38+ multiple myeloma?
Daratumumab
Elotuzumab
Panobinostat
Polatuzumab Vedotin
Current Progress,
0 of 13 answered