Challenging Case - Pruritus in Chronic Kidney Disease: Updated Guidance for Nephrology Clinicians

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A. Start ondansetron at 8 mg PO TID

B. Start gabapentin at 300 mg PO TID

C. Start pregabalin 25 mg daily (after HD on dialysis days)

D. Start diphenhydramine 25mg for her to take as needed

E. Recommend that she start peritoneal dialysis (PD)

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Low

A. CKD-aP is more prevalent in patients with CKD than depression

B. CKD-aP has been shown to be due to hyperparathyroidism

C. CKD-aP has been shown to have no impact on quality of life in patients with ESKD or CKD

D. CKD-aP is a symptom that patients with kidney disease viewed as a low priority for research.

E. CKD-aP was found to be present in approximately 20% of patients with ESKD on HD

High

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A. Naltrexone

B. Gabapentin

C. Pregabalin

D. Difelikefalin

E. None of the above

High

Medium

Low