Pediatric Grand Rounds Evaluation 11/6/2024 (MOC) Title: Current Developments in Pulmonary Gene TherapySpeaker(s):David Dean, PhDProfessor, Departments of Pediatrics, Biomedical Engineering, and Pharmacology & Physiology University of Rochester Medical CenterLearning Objectives:1. Name two diseases with FDA-approved gene therapy treatments.2. Describe the pathway for intracellular movement of DNA during gene therapy.3. Describe the benefits of electroporation for gene delivery. Question Title * 1. Date of Presentation Question Title * 2. Your First Name: Question Title * 3. Your Last Name: Question Title * 4. Your Email Address: Question Title * 5. Month and Day of your Birth Month: Day: Question Title * 6. Your Professional Category MD/DO PhD PA NP RN Other (please specify) Question Title * 7. Please rate the impact of the following course objectivesAs a result of attending this activity, I am better able to: Strongly Agree Agree Disagree Strongly Disagree 1. Name two diseases with FDA-approved gene therapy treatments. 1. Name two diseases with FDA-approved gene therapy treatments. Strongly Agree 1. Name two diseases with FDA-approved gene therapy treatments. Agree 1. Name two diseases with FDA-approved gene therapy treatments. Disagree 1. Name two diseases with FDA-approved gene therapy treatments. Strongly Disagree 2. Describe the pathway for intracellular movement of DNA during gene therapy. 2. Describe the pathway for intracellular movement of DNA during gene therapy. Strongly Agree 2. Describe the pathway for intracellular movement of DNA during gene therapy. Agree 2. Describe the pathway for intracellular movement of DNA during gene therapy. Disagree 2. Describe the pathway for intracellular movement of DNA during gene therapy. Strongly Disagree 3. Describe the benefits of electroporation for gene delivery. 3. Describe the benefits of electroporation for gene delivery. Strongly Agree 3. Describe the benefits of electroporation for gene delivery. Agree 3. Describe the benefits of electroporation for gene delivery. Disagree 3. Describe the benefits of electroporation for gene delivery. Strongly Disagree Question Title * 8. Please rate the projected impact of this activity on your knowledge, competence, performance, and patient outcomes.*Competence is defined as the ability to apply knowledge, skills and judgement in practice (knowing how to do something) Yes No No Change The activity increased my knowledge The activity increased my knowledge Yes The activity increased my knowledge No The activity increased my knowledge No Change The activity increased my competence The activity increased my competence Yes The activity increased my competence No The activity increased my competence No Change The activity improved/will improve my performance The activity improved/will improve my performance Yes The activity improved/will improve my performance No The activity improved/will improve my performance No Change The activity will improve my patient outcome The activity will improve my patient outcome Yes The activity will improve my patient outcome No The activity will improve my patient outcome No Change If you answer "yes" to any of the items above, please describe: Question Title * 9. Please rate the speaker on knowledge/content of the presentation Excellent Above Average Average Below Average Poor Rating: Rating: Excellent Rating: Above Average Rating: Average Rating: Below Average Rating: Poor Comments: Question Title * 10. Do you feel this activity was free of commercial bias or influence?*Commercial bias is defined as a personal judgment in favor of specific product or service of a commercial interest Yes No (please explain) Comment: Question Title * 11. Do you feel this activity was evidence-based? Yes No (please explain) Comment: Question Title * 12. Do you plan to make changes to your practice as a result of attending this activity? Yes No (please explain) N/A (I do not work with patients) If yes, please explain with examples. If no, please indicate any perceived barriers to implementing changes. Question Title * 13. Please list suggestions you have for future topics as well as any addition comments. Question Title * 14. Are you claiming MOC credit? Yes No If you are not requesting MOC, please scroll to the end of the survey. Otherwise, please check the following attestation and provide your ABP ID number below: Question Title * 15. "I give permission to the University of Rochester to share my MOC completion data with the Accreditation Council for Continuing Medical Education (ACCME) and the American Board of Pediatrics (ABP) and transmit the completion data to the ACCME's PARS System on my behalf." Yes No Question Title * 16. Your ABP ID Number: In order to receive MOC credit for Grand Rounds, please fill out the correct answers to the two questions below. Credit will be awarded when one of the two questions have been answered correctly. Question Title * 17. Gene therapy has not found greater clinical success due primarily to issues with: a) Choosing the correct gene to overexpress or silence. b) Effective delivery of genes. c) The high cost of treatment Question Title * 18. How does the beta 1 subunit of the Na,K-ATPase act to treat acute lung injury? a) Increase alveolar fluid clearance from the lung b) Increase alveolar-capillary barrier function c) All of the above AccreditationThe University of Rochester School of Medicine and Dentistry is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physiciansCertificationThe University of Rochester School of Medicine and Dentistry designates this live activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Maintenance of Certification(MOC)Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to 1 MOC point in the American Board of Pediatrics' (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit. Done