NBCC LEADcast Quiz - Dr. Keith Knutson [QUIZ MODE TEST]

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* 1. True or False: The adaptive immune system is the non-specific, first line of defense against foreign invaders and includes the epithelial and mucosal linings of our respiratory and GI tracts, as well as our skin.

True

False

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* 2. Which of the following immune cells are NOT part of the adaptive immune system?

CD4 “helper” T cells

CD8 “cytolytic” T cells

B cells

Macrophages

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* 3. True or False: One teaspoon of blood contains approximately 12 million unique T and B cells.

True

False

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* 4. Immune-based approaches for cancer include all but which of the following methods?

Monoclonal and other antibodies (e.g., HER2 antibodies like Herceptin)

Adoptive T cell therapies

Chemotherapy

Pembrolizumab

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* 5. True or False: Vaccination is used to heighten the sensitivity of the immune system to tumor antigens using immunologic memory.

True

False

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* 6. Which of the following does not represent a mutation-derived neoantigen choice for a cancer vaccine?

Microbial neoantigen

Amino acid mutation neoantigen

Frameshift / fusion neoantigen

Splicing variant neoantigen

Indel neoantigen

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* 7. Which of the following antigens is important in triple negative breast cancer?

Folate receptor alpha

HER2/neu

Modified vaccinia virus Ankara

TNBC beta