Current approach on COVID-19 and other vaccinations in previous MIS-C/PIMS: a MAS/sJIA and Vaccination WPs survey

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* 1. Which is your country of practice?

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* 2. Which is your center of practice?

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* 3. Which is your area of expertise?

general pediatrics

pediatric rheumatology

pediatric infectious disease

pediatric immunology

pediatric emergency care

pediatric cardiology

Other (please specify)

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* 4. How many patients with MIS-C/PIMS have been treated in your centre?

< 5

5-20

20-50

> 50

data not available

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* 5. Is anti SARS-CoV-2 vaccine available for children in your country?

yes, for children > 16 years old

yes, for children > 12 years old

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* 6. Have you vaccinated any children with previous MIS-C/PIMS with anti SARS-CoV-2 vaccine at your centre?

Yes

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* 7. If you answered yes to Question 6, how many children with previous MIS-C/PIMS have you vaccinated with anti SARS-CoV-2 vaccine at your centre?

5-10

> 10

data not available

Not applicable

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* 8. If you answered yes to Question 6, did you observe any side effects after anti SARS-CoV-2 vaccine in patients with previous MIS-C/PIMS?

Yes

data not available

Not applicable

If yes, please specify:

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* 9. How many patients of yours with previous MIS-C/PIMS got COVID-19 infection again?

None

2-5

data not available

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* 10. If you answered yes to Question 9, how many of them did present a MIS-C/PIMS relapse?

None

2-5

data not available

Not applicable

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* 11. If you vaccinated or aim to vaccinate with anti SARS-CoV-2 vaccine patients with previous MIS-C/PIMS, what would, in your opinion, be a reasonable timing for the 1st booster vaccination?

between 3-6 months after MIS-C/PIMS

between 6-12 months after MIS-C/PIMS

later than 12 months after MIS-C/PIMS

I will not vaccinate patients with previous MISC/PIMS

Comments:

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* 12. Which variables do impact on your decision not to vaccinate with anti SARS-CoV-2 vaccine a patient with previous MIS-C/PIMS? (multiple choice possible)

current lack of evidence

fear of relapse

patient/parent decision

local specific recommendation against

ongoing immunosuppressive treatment

presence of still positive SARS-CoV-2 serology

excessive proximity to MIS-C/PIMS episode

history of severe MISC/PIMS

history of severe MISC/PIMS with myocarditis

Other (please specify)

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* 13. Which variables do you consider most relevant in your decision to vaccinate with anti SARS-CoV-2 vaccine a patient with previous MIS-C/PIMS? (multiple choice possible)

time from MIS-C/PIMS episode

SARS-CoV-2 serologic status

ongoing immunosuppressive treatment

MIS-C/PIMS features

Other or comments (please specify)

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* 14. Would you consider to continue regular vaccinations with non-live vaccines according to the national vaccination program in a child with previous MIS-C/PIMS?

Yes

Yes, but not before 3 months after MIS-C/PIMS

Yes, but not before 6 months after MIS-C/PIMS

Yes, but not before 12 months after MIS-C/PIMS

Comments:

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* 15. Would you consider to continue regular vaccinations with live attenuated vaccines according to the national vaccination program in a child with previous MIS-C/PIMS?

Yes

Yes, but not before 3 months after MIS-C/PIMS

Yes, but not before 6 months after MIS-C/PIMS

Yes, but not before 12 months after MIS-C/PIMS

Comments: