Screen Reader Mode Icon

Purpose of the survey

The purpose of this survey is to identify key areas of focus for the HESI Bioaccumulation Committee to evaluate and potentially address.  This may lead to a re-focus of the goals and objectives of the group, given advances since the committee was formed in 2004.

Of particular interest are how bioaccumulation data (specifically) and toxicokinetic (TK) data (more broadly) are currently used in the ecological risk assessment context.  TK describes and quantifies the processes and rates of chemical absorption, distribution, metabolism (biotransformation) and elimination (ADME) in an organism. These biokinetic processes play an important role in ecological (and human health) assessments by influencing a substance’s fate, exposure, bioaccumulation, and toxicity. 

Moving beyond “B’ criteria, we are interested in exploring how both bioaccumulation and TK (ADME) data are currently used to inform chemical evaluations, whether they could be used more effectively, what scientific gaps need to be filled, and how the broader ecological assessment framework can be enhanced / modified.    

Overall, the ultimate goal is to improve and strengthen the science that underpins effective ecological assessment in a fit-for-purpose, resource appropriate manner.

This survey will take you about 10 minutes, but you will be able to save your progress, and complete it at a later time.

Finally, note that your name and contact information will be used for internal purpose only, and will not be shared with anyone. 

Question Title

* 1. First Name

Question Title

* 2. Last Name

Question Title

* 3. Email address

Question Title

* 4. Affiliation

Question Title

* 5. Sector of activity

Question Title

* 6. Check the boxes what describe you

Question Title

* 7. What kind of bioaccumulation or TK (ADME) data are you most interested in?

Question Title

* 8. In what context do you use bioaccumulation and/or TK (ADME) data?

Question Title

* 9. Based on your experience, how much are the different aspects of TOXICOKINETICS (ADME) outlined in the first row (In silico, in vitro approaches…etc.) used in practice to inform the areas listed in the first column. (Please, scroll to the right to see the entire table.)

  In silico (Aquatic organisms) In vitro (Aquatic organisms) In vivo (Aquatic organisms) Field (Aquatic organisms) In silico (Terrestrial organisms) In vitro (Terrestrial organisms) In vivo (Terrestrial organisms) Field (Terrestrial organisms)
PBT Classification
Screening
Prioritization
Ecological risk assessment
Human health risk assessment

Question Title

* 10. For those categories that you ranked as “never used” and “sometimes used”, please indicate the potential  reasons as listed below.

Question Title

* 11. If you had TOXICOKINETIC (ADME) data how would you use it? (or if you currently use TK data, how do you use it?)

Question Title

* 12. What specific developments would be needed to realize the full potential of TOXICOKINETIC data?

Question Title

* 13. Based on your experience, how much are the different aspects of BIOACCUMULATION science outlined in the first row (In silico, in vitro approaches…etc.) used in practice to inform the areas listed in the first column.

  In silico (Aquatic organisms) In vitro (Aquatic organisms) In vivo (Aquatic organisms) Field (Aquatic organisms) In silico (Terrestrial organisms) In vitro (Terrestrial organisms) In vivo (Terrestrial organisms) Field (Terrestrial organisms)
PBT Classification
Screening
Prioritization
Ecological risk assessment
Human health risk assessment

Question Title

* 14. For those categories that you ranked as “never used” and “sometimes used”, please indicate the potential  reasons as listed below.

Question Title

* 15. What specific developments would be needed to realize the full potential of BIOACCUMULATION data?

Question Title

* 16. Tell us about modeling

Question Title

* 17. Do you have any additional comments or questions?

0 of 17 answered
 

T