Survey of the ISEV Translation, Regulation and Advocacy Committee

With this survey of 25 questions (some optional), ISEV's new Translation, Regulation, and Advocacy Committee would like to get your feedback on the degree to which EVs have been translated, awareness of EV potential, and the uses of EVs in different industry sectors. We would also like to know your expectations and suggestions for the new Committee. Information provided here may be made freely available to assist with reinforcing and promoting EV research and applications.

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* 1. Please enter the following information. By providing an email address, you consent to being contacted for follow-up if needed.

First (or given) name

Last (or family) name

Email address

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* 2. Are you an ISEV member?

I am currently an ISEV member

I am not currently, but have previously been an ISEV member

I am not and have not previously been an ISEV member

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* 3. If you are currently employed in academia, what is your position? (Please also complete this question if you are employed by both academia and industry.)

 Principal Investigator

 Research assistant (or any staff scientist position)

 Postdoc

 PhD student

 Technician

Other (please specify)

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* 4. If you completed Question 3, above, what academic institution do you work for? (Institution, City, Country)

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* 5. If you are currently employed in industry, what is your position? (Please also complete this question if you are employed by both academia and industry.)

CEO

CSO

Other C-suite officer

Group leader

Staff scientist

PhD student

Technician

Other (please specify)

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* 6. If you completed Question 5, above, what company do you work for? (Company, City, Country)

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* 7. If you are involved in a "spin-off" company (not listed above), please provide the following details. (A spin-off is usually a start-up company associated with findings from a specific academic lab.)

Name, City, and Country

Year of foundation

Is it primarily EV focused? (YES/NO)

If not primarily EV-focused, are EVs involved? (YES/NO)

Webpage

Brief description or comments

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* 8. If you do not work in academia or industry, please describe your current role: position title, organization, city, country.

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* 9. Are you part of an advisory board, or do you otherwise advise, any company?

Yes (if so, please disclose the company or companies)

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* 10. In what area(s) of EV research are you actively working? (Please tick a maximum of four.)

Fundamental mechanisms of EV biology

Diagnostic applications

Therapeutic applications (using native or engineered EVs as a therapy)

EV-based drug delivery systems

Food/dietary or agriculture applications

Ecological application

Cosmetic applications

Other (please specify)

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* 11. Which area(s) of EV research are you INTERESTED in but do not WORK on currently? (Please tick a maximum of four.)

Fundamental mechanisms of EV biology

Diagnostic applications

Therapeutic applications (using native or engineered EVs as a therapy)

EV-based drug delivery systems

Food/dietary or agriculture applications

Ecological application

Cosmetic applications

Other (please specify)

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* 12. Do you have a patent, patents, or patent applications related to EVs? If so, please indicate designation, title, and details (this information might be placed in a database or on the ISEV website).

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* 13. Are you involved in any clinical trial(s) related to EVs? If so, please indicate designation, title, and details (this information might be placed in a database or on the ISEV website).

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* 14. What companies are you aware of that claim to use EVs (including exosomes or similar) as products? If so, please provide name(s) and website(s).

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* 15. What companies are you aware of that sell EVs (including exosomes or similar) for use in research? If so, please provide name(s) and website(s).

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* 16. Have you bought EVs or EV-containing products? If so, please give the product(s) as well the source company name(s) and website(s).

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* 17. Are you aware of companies or agencies that specialize in navigating and managing regulatory processes (e.g., in diagnostics, therapeutics, cosmetics, environmental applications)? If so, please provide name(s), website(s), and any details.

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* 18. What major sources of PUBLIC funding for EV product development are you aware of?

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* 19. What major sources of PRIVATE funding for EV product development are you aware of?

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* 20. What are the major obstacles that you see for EV translation (please provide a list).

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* 21. What types of products would you like or expect from ISEV's new Translation, Regulation, and Advocacy Committee? (Tick a maximum of 5.)

Reports and graphics of the overall EV marketplace (freely available to be used in presentations and be referenced)

Reports and graphics of the degree of translation of existing EV products (freely available to be used in presentations and be referenced)

A checklist of what is needed to translate an EV product (possibly sector-specific)

List of companies selling material/instruments of interest for EV research, with the main characteristics

List of companies selling material/instruments of interest for EV clinical applications, with the main characteristics

List of clinical trials based on EVs

List of patents based on EVs

List of EV products that are already on the market

Accounts of how previous products received regulatory approval

Opinions/interviews with experts pointing to possible opportunities for EVs in new sectors

Other (please specify)

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* 22. ISEV discussions of EV applications are usually focused on human or veterinary clinical applications. In your view, should ISEV also discuss any of the following applications? First, what about the cosmetics industry?

Yes

Comments?

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* 23. Second, what about the agriculture and/or food industry?

Yes

Comments?

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* 24. Third, what about environmental applications (not including agriculture, above)?

Yes

Comments?

Survey of the ISEV Translation, Regulation and Advocacy Committee

Question Title

* 1. Please enter the following information. By providing an email address, you consent to being contacted for follow-up if needed.

Question Title

* 2. Are you an ISEV member?

Question Title

* 3. If you are currently employed in academia, what is your position? (Please also complete this question if you are employed by both academia and industry.)

Question Title

* 4. If you completed Question 3, above, what academic institution do you work for? (Institution, City, Country)

Question Title

* 5. If you are currently employed in industry, what is your position? (Please also complete this question if you are employed by both academia and industry.)

Question Title

* 6. If you completed Question 5, above, what company do you work for? (Company, City, Country)

Question Title

* 7. If you are involved in a "spin-off" company (not listed above), please provide the following details. (A spin-off is usually a start-up company associated with findings from a specific academic lab.)

Question Title

* 8. If you do not work in academia or industry, please describe your current role: position title, organization, city, country.

Question Title

* 9. Are you part of an advisory board, or do you otherwise advise, any company?

Question Title

* 10. In what area(s) of EV research are you actively working? (Please tick a maximum of four.)

Question Title

* 11. Which area(s) of EV research are you INTERESTED in but do not WORK on currently? (Please tick a maximum of four.)

Question Title

* 12. Do you have a patent, patents, or patent applications related to EVs? If so, please indicate designation, title, and details (this information might be placed in a database or on the ISEV website).

Question Title

* 13. Are you involved in any clinical trial(s) related to EVs? If so, please indicate designation, title, and details (this information might be placed in a database or on the ISEV website).

Question Title

* 14. What companies are you aware of that claim to use EVs (including exosomes or similar) as products? If so, please provide name(s) and website(s).

Question Title

* 15. What companies are you aware of that sell EVs (including exosomes or similar) for use in research? If so, please provide name(s) and website(s).

Question Title

* 16. Have you bought EVs or EV-containing products? If so, please give the product(s) as well the source company name(s) and website(s).

Question Title

* 17. Are you aware of companies or agencies that specialize in navigating and managing regulatory processes (e.g., in diagnostics, therapeutics, cosmetics, environmental applications)? If so, please provide name(s), website(s), and any details.

Question Title

* 18. What major sources of PUBLIC funding for EV product development are you aware of?

Question Title

* 19. What major sources of PRIVATE funding for EV product development are you aware of?

Question Title

* 20. What are the major obstacles that you see for EV translation (please provide a list).

Question Title

* 21. What types of products would you like or expect from ISEV's new Translation, Regulation, and Advocacy Committee? (Tick a maximum of 5.)

Question Title

* 22. ISEV discussions of EV applications are usually focused on human or veterinary clinical applications. In your view, should ISEV also discuss any of the following applications? First, what about the cosmetics industry?

Question Title

* 23. Second, what about the agriculture and/or food industry?

Question Title

* 24. Third, what about environmental applications (not including agriculture, above)?

Question Title

* 25. Comments? Please include any suggestions you want to communicate to the committee.