Post Test and Evaluation Please note that to receive credit you must achieve a score of at least 70%. Certificate of Credit will be emailed within 4 weeks of successful completion of the activity. Post-Activity Test Question Title 1. Which of the following Candida species exhibits the greatest intrinsic resistance against the azoles? C. tropicalis C. glabrata C. parapsilosis C. lusitaniae Question Title 2. Mutations in the cyp51A gene in Aspergillus has been shown to be associated with resistance against: Echinocandins Polyenes Azoles Flucytosine Question Title 3. A 54-year-old female patient with AML is admitted for induction chemotherapy. She is given fluconazole and cefepime prophylaxis. Seven days later while still receiving prophylactic therapy, she develops cough, fever, and rash on her extremities. PNA-FISH analysis of a blood sample reveals the presence of Candida. Which of the following is the most appropriate option? Increase the dose of fluconazole Switch to voriconazole therapy Switch to an echinocandin Wait for susceptibility results before adjusting therapy Question Title 4. Antifungal prophylaxis with all of the following agents provides protection against molds except:? Fluconazole Voriconazole Posaconazole Micafungin Question Title 5. Appropriate samples that can be used to identify Aspergillus infection via galactomannan EIA include: Serum BAL Sputum All of the above Serum and BAL Only Question Title 6. The Fungitell Beta-D-glucan assay can be used to detect infections caused by: Cryptococcus neoformans Aspergillus spp. Zygomycetes Staphylococcus spp. Question Title 7. Therapeutic drug monitoring is recommended with the use of: Fluconazole Voriconazole Micafungin All of the above Question Title 8. IDSA currently recommends first-line treatment of pulmonary aspergillosis with: Anidulafungin Voriconazole Posaconazole Amphotericin B Question Title 9. Appropriate treatment of mucormycosis in a 24-year-old patient following an allogeneic bone marrow transplantation who is currently taking immunosuppressive medication is: Voriconazole Caspofungin High-dose lipid formulation of amphotericin B Fluconazole plus an echinocandin Question Title 10. In a clinical study comparing voriconazole with isavuconazole for the treatment of aspergillosis and mold infections, compared to voriconazole use, isavuconazole treatment was shown to result in: Significantly lower 6-week mortality rates Significantly higher success rates at end of therapy Statistically fewer drug-related adverse events All of the above Next