Title: Current Developments in Pulmonary Gene Therapy

Speaker(s)
:
Topic: The Search for Tractable Translatable Endophenotypes (Neuromarkers) in Neurodevelopment Disorders
John Foxe, PhD
Professor and Chair, Department of Neuroscience
Research Director, The Ernst J. Del Monte Institute for Neuroscience
University of Rochester Medical Center
Learning Objectives:
1. Name two diseases with FDA-approved gene therapy treatments.
2. Describe the pathway for intracellular movement of DNA during gene therapy.
3. Describe the benefits of electroporation for gene delivery.

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* 1. Date of Presentation

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* 2. Your First Name:

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* 3. Your Last Name:

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* 4. Your Email Address:

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* 5. Month and Day of your Birth

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* 6. Your Professional Category

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* 7. Please rate the impact of the following course objectives
As a result of attending this activity, I am better able to:

  Strongly Agree Agree Disagree Strongly Disagree
1. Understand the use of event-related potentials (ERPs) to assess brain activity in human clinical populations.
2. Understand the concept of an endophenotype (neuromarker)
3. Learn about sensory-perceptual functioning in Rett Syndrome, Autism and Batten Disease

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* 8. Please rate the projected impact of this activity on your knowledge, competence, performance, and patient outcomes.
*Competence is defined as the ability to apply knowledge, skills and judgement in practice (knowing how to do something)

  Yes No No Change
The activity increased my knowledge
The activity increased my competence
The activity improved/will improve my performance
The activity will improve my patient outcome

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* 9. Please rate the speaker on knowledge/content of the presentation

  Excellent Above Average Average Below Average Poor
Rating:

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* 10. Do you feel this activity was free of commercial bias or influence?
*Commercial bias is defined as a personal judgment in favor of specific product or service of a commercial interest

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* 11. Do you feel this activity was evidence-based?

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* 12. Do you plan to make changes to your practice as a result of attending this activity?

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* 13. Please list suggestions you have for future topics as well as any addition comments.

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* 14. Are you claiming MOC credit?

If you are not requesting MOC, please scroll to the end of the survey. Otherwise, please check the following attestation and provide your ABP ID number below:

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* 15. "I give permission to the University of Rochester to share my MOC completion data with the Accreditation Council for Continuing Medical Education (ACCME) and the American Board of Pediatrics (ABP) and transmit the completion data to the ACCME's PARS System on my behalf."

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* 16. Your ABP ID Number:

In order to receive MOC credit for Grand Rounds, please fill out the correct answers to the two questions below. Credit will be awarded when one of the two questions have been answered correctly.

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* 17. 1) What is an event-related potential (ERP)?

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* 18. 1) What critical cellular function do lysosomes perform?

Accreditation
The University of Rochester School of Medicine and Dentistry is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians
Certification
The University of Rochester School of Medicine and Dentistry designates this live activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Maintenance of Certification(MOC)
Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to 1 MOC point in the American Board of Pediatrics' (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

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