Post-Test, Activity Evaluation and Credit Application Form POST TEST Question Title * 1. A 59-year-old man has been hospitalized following a myocardial infarction and requires mechanical ventilation. After 4 days in the ICU, he develops fever and a chest radiograph reveals new pulmonary infiltrates. Culture from a BAL sample identifies P. aeruginosa. The ICU has experienced a recent outbreak of multidrug-resistant P. aeruginosa exhibiting upregulation of MexAB. Which of the following antimicrobials would be most likely to retain activity against this pathogen? Cefepime Piperacillin-tazobactam Ceftolozane-tazobactam Aztreonam Question Title * 2. Inducible AmpC producers will typically exhibit initial susceptibility followed by resistance after repeated exposure to which of the following antimicrobials? Amikacin Ceftazidime Imipenem Gentamicin Question Title * 3. According to the latest IDSA treatment guidance, preferred antimicrobial therapy for bacteremia caused by an organism with a high risk of inducible AmpC production (e.g., E. cloacae) is: Ceftriaxone Piperacillin-tazobactam Cefepime Aztreonam Question Title * 4. Which of the following newer antimicrobials exhibits in vitro activity against organisms that produce a metallo-beta-lactamase? Plazomicin Ceftazidime-avibactam Meropenem-vaborbactam Cefiderocol Question Title * 5. During microbiologic screening for resistant phenotypes, an ESBL-producing organism will demonstrate diminished susceptibility to which of the following classes of antimicrobials? Third-generation cephalosporins Fourth-generation cephalosporins Carbapenems All of the above Next